Dear colleagues, the journal Centro Agrícola begins 2019 in volume 46. Attractive results on Metarhizium anisopliae, the vascular wilt of Solanum quitoense and the effect of two systems of minimum tillage on soil moisture, are exposed in the same. Subjects as diverse as the evaluation of fertilizers mixed with zeolite, the effectiveness of Singular 350 SC, the effect of Mancozeb 80 PH on the appearance of the green spot, the medicinal potentialities of weeds, as well as the severity of phosphorus deficiency in the strawberry crop, can also be found in this issue. Likewise, the communication "Agrotourism, a vision from sustainable development" is suggested. The content of this issue closes a brief communication referring to multimedia: "Catalog of Cuban varieties of sugar cane".